Alexidine

Alexidine is an antimicrobial of the biguanide class.[1] It is also a bisbiguanide.[2]

Alexidine

Names
IUPAC name 1,1’-(1,6-Hexanediyl)bis{2-[N’-(2-ethylhexyl)carbamimidoyl]guanidine}
Identifiers
CAS Number	22573-93-9^Y
3D model (JSmol)	Interactive image
ChEBI	CHEBI:CHEBI:53661
ChEMBL	ChEMBL1195210
ChemSpider	2006
ECHA InfoCard	100.040.981
EC Number	245-096-7
KEGG	D02804
PubChem CID	2090
UNII	GVN71CAL3G^Y
CompTox Dashboard (EPA)	DTXSID4048482
InChI InChI=1S/C26H56N10/c1-5-9-15-21(7-3)19-33-25(29)35-23(27)31-17-13-11-12-14-18-32-24(28)36-26(30)34-20-22(8-4)16-10-6-2/h21-22H,5-20H2,1-4H3,(H5,27,29,31,33,35)(H5,28,30,32,34,36) Key: LFVVNPBBFUSSHL-UHFFFAOYSA-N InChI=1/C26H56N10/c1-5-9-15-21(7-3)19-33-25(29)35-23(27)31-17-13-11-12-14-18-32-24(28)36-26(30)34-20-22(8-4)16-10-6-2/h21-22H,5-20H2,1-4H3,(H5,27,29,31,33,35)(H5,28,30,32,34,36) Key: LFVVNPBBFUSSHL-UHFFFAOYAY
SMILES CCCCC(C/N=C(/N=C(\NCCCCCCN/C(=N\C(=N\CC(CCCC)CC)\N)/N)/N)\N)CC
Properties
Chemical formula	C26H56N10
Molar mass	508.804 g·mol^−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

References

1. "Antimicrobial substantivity of alexidine and chlorhexidine in dentin". J Endod. 39 (11): 1413–5. November 2013. doi:10.1016/j.joen.2013.07.038. PMID 24139264.
2. Tanzer JM, Slee AM, Kamay BA (1977). "Structural requirements of guanide, biguanide, and bisbiguanide agents for antiplaque activity". Antimicrob. Agents Chemother. 12 (6): 721–9. doi:10.1128/aac.12.6.721. PMC 430011. PMID 931371.