Alaninol

Alaninol is the organic compound with the formula CH3CH(NH2)CH2OH. A colorless solid, the compound is classified as an amino alcohol. It can be generated by converting the carboxylic group of alanine to an alcohol with a strong reducing agent such as lithium aluminium hydride,[1]. The compound is chiral, and as is normal for chiral compounds, the physical propertiies of the racemate differ somewhat from those of the enantiomers. It is a precursor to numerous chiral ligands used in asymmetric catalysis.[2]

Alaninol
Names
IUPAC name
(2S)-2-Aminopropan-1-ol
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard 100.018.535
EC Number
  • 220-388-7
UNII
Properties
C3H9NO
Molar mass 75.111 g·mol−1
Appearance colorless solid
Melting point 96 °C racemate
72-72 °C for R or S
Boiling point 174.5 °C (346.1 °F; 447.6 K)
Hazards
GHS pictograms
GHS Signal word Danger
GHS hazard statements
H314
P260, P264, P280, P301+330+331, P303+361+353, P304+340, P305+351+338, P310, P321, P363, P405, P501
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

References

  1. Dickman, D.A.; Meyers, A.I.; Smith, G.A.; Gawley, R.E. (1990). "Reduction of α-Amino Acids". Organic Syntheses. 7: 530. doi:10.15227/orgsyn.063.0136. Archived from the original on 15 January 2011. Retrieved 11 October 2012.
  2. Dawson, Graham J.; Frost, Christopher G.; Williams, Jonathan M.J.; Coote, Steven J. (1993). "Asymmetric palladium catalysed allylic substitution using phosphorus containing oxazoline ligands". Tetrahedron Letters. 34 (19): 3149–3150. doi:10.1016/S0040-4039(00)93403-8.
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