Acidic leucine-rich nuclear phosphoprotein 32 family member A

Acidic leucine-rich nuclear phosphoprotein 32 family member A is a protein that in humans is encoded by the ANP32A gene.[3][4][5] It is one of the targets of an oncomiR, MIRN21.

ANP32A
Available structures
PDBHuman UniProt search: PDBe RCSB
Identifiers
AliasesANP32A, C15orf1, HPPCn, I1PP2A, LANP, MAPM, PHAP1, PHAPI, PP32, acidic nuclear phosphoprotein 32 family member A
External IDsOMIM: 600832 HomoloGene: 133783 GeneCards: ANP32A
Gene location (Human)
Chr.Chromosome 15 (human)[1]
Band15q23Start68,778,535 bp[1]
End68,820,897 bp[1]
RNA expression pattern




More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

8125

n/a

Ensembl

ENSG00000140350

n/a

UniProt

P39687

n/a

RefSeq (mRNA)

NM_006305

n/a

RefSeq (protein)

NP_006296

n/a

Location (UCSC)Chr 15: 68.78 – 68.82 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

Interactions

Acidic leucine-rich nuclear phosphoprotein 32 family member A has been shown to interact with MAP1B,[6] TAF1A[7] and Protein SET.[7][8]

See also

References

  1. GRCh38: Ensembl release 89: ENSG00000140350 - Ensembl, May 2017
  2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. Chen TH, Brody JR, Romantsev FE, Yu JG, Kayler AE, Voneiff E, Kuhajda FP, Pasternack GR (March 1997). "Structure of pp32, an acidic nuclear protein which inhibits oncogene-induced formation of transformed foci". Mol Biol Cell. 7 (12): 2045–56. doi:10.1091/mbc.7.12.2045. PMC 276049. PMID 8970164.
  4. Ulitzur N, Humbert M, Pfeffer SR (June 1997). "Mapmodulin: a possible modulator of the interaction of microtubule-associated proteins with microtubules". Proc Natl Acad Sci U S A. 94 (10): 5084–9. Bibcode:1997PNAS...94.5084U. doi:10.1073/pnas.94.10.5084. PMC 24635. PMID 9144194.
  5. "Entrez Gene: ANP32A Acidic (leucine-rich) nuclear phosphoprotein 32 family, member A".
  6. Opal, Puneet; Garcia Jesus J; Propst Friedrich; Matilla Antoni; Orr Harry T; Zoghbi Huda Y (September 2003). "Mapmodulin/leucine-rich acidic nuclear protein binds the light chain of microtubule-associated protein 1B and modulates neuritogenesis". J. Biol. Chem. 278 (36): 34691–9. doi:10.1074/jbc.M302785200. ISSN 0021-9258. PMID 12807913.
  7. Seo, S B; McNamara P; Heo S; Turner A; Lane W S; Chakravarti D (January 2001). "Regulation of histone acetylation and transcription by INHAT, a human cellular complex containing the set oncoprotein". Cell. 104 (1): 119–30. doi:10.1016/S0092-8674(01)00196-9. ISSN 0092-8674. PMID 11163245.
  8. Fan, Zusen; Beresford Paul J; Zhang Dong; Lieberman Judy (April 2002). "HMG2 interacts with the nucleosome assembly protein SET and is a target of the cytotoxic T-lymphocyte protease granzyme A". Mol. Cell. Biol. 22 (8): 2810–20. doi:10.1128/MCB.22.8.2810-2820.2002. ISSN 0270-7306. PMC 133744. PMID 11909973.

Further reading

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