AKAP2

A-kinase anchor protein 2 is an enzyme that in humans is encoded by the AKAP2 gene.[3][4]

AKAP2
Identifiers
Aliases	AKAP2, AKAP-2, AKAPKL, PRKA2, A-kinase anchoring protein 2, MISP2
External IDs	MGI: 1306795 HomoloGene: 100376 GeneCards: AKAP2
Orthologs
Species	Human	Mouse
Entrez	11217	11641
Ensembl	n/a	n/a
UniProt	Q9Y2D5	O54931
RefSeq (mRNA)	NM_001198656 NM_001004065 NM_001136562	NM_001035532 NM_001035533 NM_009649
RefSeq (protein)	NP_009134 NP_671492	NP_033779 NP_001291473 NP_766456
Location (UCSC)	n/a	n/a
PubMed search	[1]	[2]
Wikidata
View/Edit Human View/Edit Mouse

Interactions

AKAP2 has been shown to interact with PRKAR2A.[5][6]

References

1. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
2. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. Nagase T, Ishikawa K, Suyama M, Kikuno R, Hirosawa M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Jul 1999). "Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 6 (1): 63–70. doi:10.1093/dnares/6.1.63. PMID 10231032.
4. "Entrez Gene: AKAP2 A kinase (PRKA) anchor protein 2".
5. Alto NM, Soderling SH, Hoshi N, Langeberg LK, Fayos R, Jennings PA, Scott JD (Apr 2003). "Bioinformatic design of A-kinase anchoring protein-in silico: a potent and selective peptide antagonist of type II protein kinase A anchoring". Proc. Natl. Acad. Sci. U.S.A. 100 (8): 4445–50. doi:10.1073/pnas.0330734100. PMC 153575. PMID 12672969.
6. Dong F, Feldmesser M, Casadevall A, Rubin CS (Mar 1998). "Molecular characterization of a cDNA that encodes six isoforms of a novel murine A kinase anchor protein". J. Biol. Chem. 273 (11): 6533–41. doi:10.1074/jbc.273.11.6533. PMID 9497389.

External links

• Human AKAP2 genome location and AKAP2 gene details page in the UCSC Genome Browser.

Further reading

• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Alto NM, Soderling SH, Hoshi N, et al. (2003). "Bioinformatic design of A-kinase anchoring protein-in silico: a potent and selective peptide antagonist of type II protein kinase A anchoring". Proc. Natl. Acad. Sci. U.S.A. 100 (8): 4445–50. doi:10.1073/pnas.0330734100. PMC 153575. PMID 12672969.
• Kammerer S, Burns-Hamuro LL, Ma Y, et al. (2003). "Amino acid variant in the kinase binding domain of dual-specific A kinase-anchoring protein 2: a disease susceptibility polymorphism". Proc. Natl. Acad. Sci. U.S.A. 100 (7): 4066–71. doi:10.1073/pnas.2628028100. PMC 153049. PMID 12646697.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Hu B, Copeland NG, Gilbert DJ, et al. (2001). "The paralemmin protein family: identification of paralemmin-2, an isoform differentially spliced to AKAP2/AKAP-KL, and of palmdelphin, a more distant cytosolic relative". Biochem. Biophys. Res. Commun. 285 (5): 1369–76. doi:10.1006/bbrc.2001.5329. PMID 11478809.
• Dong F, Feldmesser M, Casadevall A, Rubin CS (1998). "Molecular characterization of a cDNA that encodes six isoforms of a novel murine A kinase anchor protein". J. Biol. Chem. 273 (11): 6533–41. doi:10.1074/jbc.273.11.6533. PMID 9497389.