AGTPBP1 (gene)

ATP/GTP binding protein 1 is a protein that in humans is encoded by the AGTPBP1 gene. [5]

AGTPBP1
Identifiers
Aliases	AGTPBP1, CCP1, NNA1, ATP/GTP binding protein 1, CONDCA
External IDs	OMIM: 606830 MGI: 2159437 HomoloGene: 9067 GeneCards: AGTPBP1
Gene location (Human) Chr. Chromosome 9 (human)[1] Band 9q21.33 Start 85,546,539 bp[1] End 85,742,029 bp[1]
Gene location (Mouse) Chr. Chromosome 13 (mouse)[2] Band 13 B2|13 Start 59,445,742 bp[2] End 59,585,227 bp[2]
Gene ontology Molecular function • carboxypeptidase activity • tubulin binding • zinc ion binding • peptidase activity • metallopeptidase activity • hydrolase activity • metal ion binding • metallocarboxypeptidase activity Cellular component • cytoplasm • cytosol • mitochondrion • cell nucleus • nucleolus • intracellular membrane-bounded organelle Biological process • mitochondrion organization • olfactory bulb development • C-terminal protein deglutamylation • neuromuscular process • eye photoreceptor cell differentiation • protein side chain deglutamylation • proteolysis • cerebellar Purkinje cell differentiation Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	23287	67269
Ensembl	ENSG00000135049	ENSMUSG00000021557
UniProt	Q9UPW5	Q641K1
RefSeq (mRNA)	NM_001286715 NM_001286717 NM_015239 NM_001330701	NM_001048008 NM_001284218 NM_001284219 NM_001284221 NM_023328 NM_001377097
RefSeq (protein)	NP_001273644 NP_001273646 NP_001317630 NP_056054 NP_056054.2	NP_001041473 NP_001271147 NP_001271148 NP_001271150 NP_075817 NP_001364026
Location (UCSC)	Chr 9: 85.55 – 85.74 Mb	Chr 13: 59.45 – 59.59 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

Function

NNA1 is a zinc carboxypeptidase that contains nuclear localization signals and an ATP/GTP-binding motif that was initially cloned from regenerating spinal cord neurons of the mouse.[supplied by OMIM, Jul 2002].

References

1. GRCh38: Ensembl release 89: ENSG00000135049 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000021557 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: ATP/GTP binding protein 1". Retrieved 2018-06-13.

Further reading

• Thakar K, Karaca S, Port SA, Urlaub H, Kehlenbach RH (March 2013). "Identification of CRM1-dependent Nuclear Export Cargos Using Quantitative Mass Spectrometry". Mol. Cell. Proteomics. 12 (3): 664–78. doi:10.1074/mcp.M112.024877. PMC 3591659. PMID 23242554.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.