AFL
Sport
- Arena Football League, a former American indoor football league
- American Football League (AFL), a name shared by several separate and unrelated professional American football leagues:
- American Football League (1926) (a.k.a. "AFL I"), first rival of the National Football League (NFL) that competed in 1926
- American Football League (1934), regional borderline-major league that competed in 1934
- American Football League (1936) (a.k.a. "AFL II"), second rival of the NFL that competed in 1936 and 1937
- American Football League (1938), minor professional American football league that changed its name to the American Professional Football Association in 1939
- American Football League (1940) (a.k.a. "AFL III"), third rival of the NFL that competed in 1940 and 1941
- American Football League (1944), offshoot of the Pacific Coast Professional Football League, played one year before merging back with the PCPFL
- American Football League (1946), name adopted by the American Association minor American football league in 1946
- American Football League (a.k.a. "AFL IV"), an American football league, active from 1960 to 1970
- Australian Football League, the top-level men's Australian rules football league
- Australian rules football, a sport commonly referred to as AFL
- AFL Women's, the top-level women's Australian rules football league
- Alberta Football League, an amateur Canadian football league
- American Fencing League, a league for amateur standard fencing competition in the United States
- Anti-Football League, an organisation that bemoans the cultural saturation of the Australian Football League
- Arizona Fall League, an American off-season instructional baseball league
- AFL (video game series), a series of Australian rules football video games
- AFL (Wii), an Australian Rules Football video game for the Nintendo Wii
- Austrian Football League, the highest league of American football in Austria
Aviation
- Aeroflot, ICAO airline code AFL
- Alta Floresta Airport, IATA airport code AFL, in Alta Floresta, Brazil
Education
- Ankara Science High School, a high school in Ankara, Turkey natively referred to as Ankara Fen Liesi
- Assessment for learning
Science and technology
- American fuzzy lop (fuzzer), a fuzzer
- Astrobiology Field Laboratory, a proposed and subsequently cancelled (unfunded) robotic rover to be sent to planet Mars
- Atrial flutter, a form of cardiac arrhythmia
Other uses
- Adaptive front light, of an automobile
- Abstract family of languages
- Academic Free License, a software license
- Aflac, American insurance company (NYSE ticker: AFL)
- Alberta Federation of Labour
- American Federation of Labor, one of the first federations of labor unions in the United States, and now part of the AFL-CIO
- Armed Forces of Liberia
- Australian Freedom League
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