ACAT2

Acetyl-CoA acetyltransferase, cytosolic, also known as cytosolic acetoacetyl-CoA thiolase, is an enzyme that in humans is encoded by the ACAT2 (acetyl-Coenzyme A acetyltransferase 2) gene[5]

ACAT2
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesACAT2, acetyl-CoA acetyltransferase 2
External IDsOMIM: 100678 MGI: 87871 HomoloGene: 55855 GeneCards: ACAT2
Gene location (Human)
Chr.Chromosome 6 (human)[1]
Band6q25.3Start159,762,045 bp[1]
End159,779,112 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

39

110460

Ensembl

ENSG00000120437

ENSMUSG00000023832

UniProt

Q9BWD1

Q8CAY6

RefSeq (mRNA)

NM_005891
NM_001303253

NM_009338

RefSeq (protein)

NP_001290182
NP_005882

NP_033364

Location (UCSC)Chr 6: 159.76 – 159.78 MbChr 17: 12.94 – 12.96 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Acetyl-Coenzyme A acetyltransferase 2 is an acetyl-CoA C-acetyltransferase enzyme.

Gene

This gene shows complementary overlapping with the 3-prime region of the TCP1 gene in both mouse and human. These genes are encoded on opposite strands of DNA, as well as in opposite transcriptional orientation.[5]

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References

  1. GRCh38: Ensembl release 89: ENSG00000120437 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000023832 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: acetyl-Coenzyme A acetyltransferase 2".

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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