ABCA9

ATP-binding cassette sub-family A member 9 is a protein that in humans is encoded by the ABCA9 gene.[5]

ABCA9
Identifiers
AliasesABCA9, EST640918, ATP binding cassette subfamily A member 9
External IDsOMIM: 612507 MGI: 2386796 HomoloGene: 33332 GeneCards: ABCA9
Gene location (Human)
Chr.Chromosome 17 (human)[1]
Band17q24.2Start68,974,488 bp[1]
End69,060,949 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

10350

217262

Ensembl

ENSG00000154258

ENSMUSG00000041797

UniProt

Q8IUA7

Q8K449

RefSeq (mRNA)

NM_080283
NM_172386

NM_147220

RefSeq (protein)

NP_525022

NP_671753

Location (UCSC)Chr 17: 68.97 – 69.06 MbChr 11: 110.1 – 110.17 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Function

This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two transmembrane domains and two nucleotide binding folds. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies ( ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This gene is a member of the ABC1 subfamily and is clustered with four other ABC1 family members on chromosome 17q24. Transcriptional expression of this gene is induced during monocyte differentiation into macrophages and is suppressed by cholesterol import.[5]

gollark: I'm glad my family doesn't go for IoT things and mostly listens to me talking about the awful privacy side of them.
gollark: Oh, I meant that smart criminals might.
gollark: The fun thing about those WiFi cameras is that as far as I know WiFi devices can be deauthed or something relatively easily, so someone with... a phone and some software might work... can just make it not see anything and it'll get dismissed as a glitch.
gollark: Have you tried explaining it to them?
gollark: They'll complain, though.

References
  1. GRCh38: Ensembl release 89: ENSG00000154258 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000041797 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: ABCA9 ATP-binding cassette, sub-family A (ABC1), member 9".

Further reading
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