5-Formyluracil

5-Formyluracil
Names
	IUPAC name 2,4-Dioxo-1,2,3,4-tetrahydro-5-pyrimidinecarbaldehyde
Identifiers
CAS Number	1195-08-0;
3D model (JSmol)	Interactive image;
ChEBI	CHEBI:80961;
ChemSpider	269368;
ECHA InfoCard	100.153.693
KEGG	C17206;
PubChem CID	304590;
UNII	F2SUM4W8EB;
CompTox Dashboard (EPA)	DTXSID40922994 ;
	InChI InChI=1S/C5H4N2O3/c8-2-3-1-6-5(10)7-4(3)9/h1-2H,(H2,6,7,9,10) Key: OHAMXGZMZZWRCA-UHFFFAOYSA-N;
	SMILES O=CC1=CNC(=O)NC1=O;
Properties
Chemical formula	C5H4N2O3
Molar mass	140.098 g·mol−1
Hazards
GHS pictograms
GHS Signal word	Warning
GHS hazard statements	H315, H319, H335
GHS precautionary statements	P261, P264, P271, P280, P302+352, P304+340, P305+351+338, P312, P321, P332+313, P337+313, P362, P403+233, P405, P501
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
	Infobox references

5-Formyluracil is a heterocyclic organic base. It is produced from the oxidation of the methyl group of thymine. It is mutagenic.[1]

References

Klungland, A; Paulsen, R; Rolseth, V; Yamada, Y; Ueno, Y; Wiik, P; Matsuda, A; Seeberg, E; Bjelland, S. "5-Formyluracil and its nucleoside derivatives confer toxicity and mutagenicity to mammalian cells by interfering with normal RNA and DNA metabolism". Toxicol Lett. 119: 71–8. doi:10.1016/s0378-4274(00)00308-8. PMID 11275423.

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