4-Piperidinone
4-Piperidinone is a derivative of piperidine with the molecular formula C5H9NO. 4-Piperidone is used as an intermediate in the manufacture of chemicals and pharmaceutical drugs.
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| Names | |
|---|---|
| Preferred IUPAC name
Piperidin-4-one | |
| Other names
4-Piperidone Azinanone Azinan-4-one | |
| Identifiers | |
3D model (JSmol) |
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| ChemSpider | |
| ECHA InfoCard | 100.050.420 |
| UNII | |
CompTox Dashboard (EPA) |
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| Properties | |
| C5H9NO | |
| Molar mass | 99.133 g·mol−1 |
| Boiling point | 79 °C (174 °F; 352 K) |
| Hazards | |
EU classification (DSD) (outdated) |
Flammable (F) Harmful (Xn) Dangerous for the environment (N) |
| NFPA 704 (fire diamond) | |
| Flash point | 91 °C (196 °F; 364 K) |
| Related compounds | |
Related compounds |
Piperidine; 2-Piperidinone |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
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| Infobox references | |
Piperidones
Piperidones are a class of chemical compounds sharing the piperidone skeleton. A classic named reaction for the synthesis of piperidones is the Petrenko-Kritschenko piperidone synthesis which involves combining an alkyl-1,3-acetonedicarboxylate with benzaldehyde and an amine.[1] This multicomponent reaction is related to the Hantzsch pyridine synthesis.
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See also
References
- Ueber die Condensation von Aceton-dicarbonsäureestern mit Benzaldehyd unter Anwendung von Ammoniak P. Petrenko-Kritschenko, N. Zoneff Berichte der deutschen chemischen Gesellschaft Volume 39 Issue 2, Pages 1358 - 1361 1906 doi:10.1002/cber.19060390234
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