4-Phenyl-4-(1-piperidinyl)cyclohexanol

4-Phenyl-4-(1-piperidinyl)cyclohexanol, also known as PPC, is an organic chemical which is a metabolite of phencyclidine (PCP).[1] It can be detected in the hair of PCP users.[2]

4-Phenyl-4-(1-piperidinyl)cyclohexanol

Names
Preferred IUPAC name 4-Phenyl-4-(piperidin-1-yl)cyclohexan-1-ol
Other names 4-Phenyl-4-(1-piperidinyl)cyclohexanol
Identifiers
CAS Number	60756-83-4^Y
3D model (JSmol)	Interactive image Interactive image
ChemSpider	142418^Y
PubChem CID	162171
UNII	TAJ3PEY6RN^Y
CompTox Dashboard (EPA)	DTXSID60209577
InChI InChI=1S/C17H25NO/c19-16-9-11-17(12-10-16,15-7-3-1-4-8-15)18-13-5-2-6-14-18/h1,3-4,7-8,16,19H,2,5-6,9-14H2^Y Key: KPRUAZBLIREHPD-UHFFFAOYSA-N^Y InChI=1/C17H25NO/c19-16-9-11-17(12-10-16,15-7-3-1-4-8-15)18-13-5-2-6-14-18/h1,3-4,7-8,16,19H,2,5-6,9-14H2 Key: KPRUAZBLIREHPD-UHFFFAOYAM
SMILES OC1CCC(N2CCCCC2)(C3=CC=CC=C3)CC1 OC3CCC(c1ccccc1)(N2CCCCC2)CC3
Properties
Chemical formula	C17H25NO
Molar mass	259.391 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is ^YN ?)
Infobox references

PPC has been shown to cause increases in locomotor activity in lab mice.[3]

See also

• PCHP, another PCP metabolite

References

1. Nabeshima, Toshitaka; Yamaguchi, Kazumasa; Fukaya, Hiroaki; Hiramatsu, Masayuki; Furukawa, Hiroshi; Kameyama, Tsutomu (1985). "Simultaneous determination of phencyclidine and its major metabolites in biological samples by high-performance liquid chromatography". Research Communications in Substances of Abuse. 6 (2): 65–78.
2. Nakahara, Yuji; Takahashi, Kazunori; Sakamoto, Tomoaki; Tanaka, Akira; Hill, Virginia A.; Baumgartner, Werner A. (1997). "Hair analysis for drugs of abuse XVII. Simultaneous detection of PCP, PCHP, and PCPdiol in human hair for confirmation of PCP use". Journal of Analytical Toxicology. 21 (5): 356–362. doi:10.1093/jat/21.5.356. PMID 9288587.
3. "Behavioral effects of phencyclidine and its major metabolite, (trans)4-phenyl-4-(1-piperidinyl)cyclohexanol, in mice".