2018 US Open – Wheelchair Women's Singles
Yui Kamiji was the defending champion, but lost to Diede de Groot in the final.
| Wheelchair Women's Singles | |
|---|---|
| 2018 US Open | |
| Champion |  |
| Runner-up |  |
| Final score | 6–2, 6–3 |
Diede de Groot won her first title, defeating Yui Kamiji in the final, 6–2, 6–3.
Seeds
Draw
Key
- Q = Qualifier
- WC = Wild Card
- LL = Lucky Loser
- Alt = Alternate
- SE = Special Exempt
- PR = Protected Ranking
- ITF = ITF entry
- JE = Junior Exempt
- w/o = Walkover
- r = Retired
- d = Defaulted
Bracket
| Quarterfinals | Semifinals | Final | ||||||||||||||||||
| 1 | | 6 | 6 | |||||||||||||||||
| 1 | 2 | ||||||||||||||||||
| 1 | | 6 | 6 | |||||||||||||||||
 | 0 | 3 | ||||||||||||||||||
| WC |  | 1 | 2 | |||||||||||||||||
| 6 | 6 | ||||||||||||||||||
| 1 | | 6 | 6 | |||||||||||||||||
| 2 | | 2 | 3 | |||||||||||||||||
 | 6 | 6 | ||||||||||||||||||
 | 4 | 4 | ||||||||||||||||||
| 1 | 0 | ||||||||||||||||||
| 2 | | 6 | 6 | |||||||||||||||||
| 0 | 0 | ||||||||||||||||||
| 2 | | 6 | 6 | |||||||||||||||||
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