2-Bromothiophene
2-Bromothiophene is an organosulfur compound with the formula C4H3BrS. It is a colorless liquid. Unlike 3-bromothiophene, the 2-bromo isomer is prepared directly by partial bromination of thiophene. It is a precursor to several drugs, including tipepidine, ticlopidine, and clopidogrel.[1]
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Names | |
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Preferred IUPAC name
2-Bromothiophene | |
Other names
2-Thienyl bromide, 2BT | |
Identifiers | |
3D model (JSmol) |
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ChemSpider | |
ECHA InfoCard | 100.012.454 |
EC Number |
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PubChem CID |
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CompTox Dashboard (EPA) |
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Properties | |
C4H3BrS | |
Molar mass | 163.03 g·mol−1 |
Appearance | Colorless liquid |
Density | 1.684 g/mL |
Melting point | −10 °C (14 °F; 263 K) |
Boiling point | 153.5 °C (308.3 °F; 426.6 K) |
Immiscible | |
Hazards | |
Main hazards | N,Xi,Xn,T |
GHS pictograms | ![]() ![]() ![]() ![]() |
GHS Signal word | Danger |
GHS hazard statements |
H226, H300, H301, H310, H315, H318, H319, H330 |
P210, P233, P240, P241, P242, P243, P260, P262, P264, P270, P271, P280, P284, P301+310, P302+350, P302+352, P303+361+353, P304+340, P305+351+338, P310, P320, P321, P322, P330, P332+313 | |
Flash point | 56 °C (133 °F; 329 K) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
Infobox references | |
Safety
The LD50 is low, 200 – 250 mg/kg (oral, rat).[1]
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gollark: Well, if we feed them on hydrogen instead, they stoichiometrically can't.
gollark: Oh, and good news, your nonexistent APIONET node is exiled until it... nonexistently has TLS support.
gollark: Well, as they say.
gollark: It would be more efficient to directly burn the food or something.
References
- Jonathan Swanston (2006). "Thiophene". Ullmann's Encyclopedia of Industrial Chemistry. Weinheim: Wiley-VCH. doi:10.1002/14356007.a26_793.pub2.
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