Eucaine
Eucaine (beta-eucaine) is a drug that was previously used as a local anesthetic.[1] It was designed as an analog of cocaine and was one of the first synthetic chemical compounds to find general use as an anesthetic.[2] It is a white, crystalline solid. Prior to World War I, Britain imported eucaine from Germany.[3] During the war, a team including Jocelyn Field Thorpe and Martha Annie Whiteley developed a synthesis in Britain.[3]
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| Trade names | Beta-Eucaine |
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| Formula | C15H21NO2 |
| Molar mass | 247.338 g·mol−1 |
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The brand name Betacaine can sometimes refer to a preparation containing lidocaine, not eucaine.
See also
- alpha-Eucaine, a related local anesthetic
References
- Walter Sneader (31 October 2005). Drug Discovery: A History. John Wiley & Sons. pp. 127–9. ISBN 978-0-470-01552-0.
- R. H. F. Manske (12 May 2014). The Alkaloids: Chemistry and Physiology. Elsevier. pp. 213–4. ISBN 978-1-4832-2192-2.
- Creese, Mary RS (1997). "Martha Annie Whiteley (1866-1956): Chemist and Editor" (PDF). Bulletin for the History of Chemistry. 8: 42–45.
External links
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