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I found a post (Windows to go usb 3.0 booting problems) which may be the answer but I wanted to throw this out there because the scenario described is not exactly the same and the error code is not mentioned there.
When I use USB 2.0 ports my IronKey device boots fine (albeit slowly). When I use either of the two USB 3.0 ports on the back of my computer I get a bluescreen and the error code 0xc00000e9. Research shows that Windows believes there is a problem with the OS's files but I believe this is incorrect because, again, it boots without a problem on USB 2.0.
Is the post I found earlier accurate for my case too or is there something else happening?
10xc00000e9 = STATUS_UNEXPECTED_IO_ERROR. Which USb 3.0 chipset do you use? – magicandre1981 – 2014-04-08T04:48:10.643