There is a number of reason, often having to do with making sure the program's memory or code isn't tampered with. Two I can think of from the top of my head:
- Copy protection. Some programs do not want you to be able to edit (or debug) the code to bypass copy protection.
- Cheat protection. Since this is a game, this is a likely reason. Running it in a virtual machine would make it easier to transparently edit values in the games memory without being detected.
- Performance. An application should generally not do this, but the programmers might have decided that running in a VM gives poor performance, such as input to screen latency, and disallows running in a VM for this reason.
Of course, just because there are legitimate reasons that the program doesn't run in a VM, doesn't mean that it is actually safe. As always, proceed with caution.
There are reasons for some applications to deny being run in VMs. What program are we talking about specifically? – gronostaj – 2013-11-21T00:38:52.103
It's a program my friend is trying to run called mapleninja. He isn't able to get it so he's trying to get me to help him. The website looks a bit fake so I'm pretty cautious about this.
– Jon – 2013-11-21T00:42:13.6173I wouldn't trust that thing as far as I could throw it. – Michael Hampton – 2013-11-21T00:52:49.763