Assuming the tools you've used have not helped, you can edit the registry direct. Please note, if you've not done this before, don't do it until you understand what the registry does and what affects of getting the below (which is untested) wrong could mean!
Windows Instant Scanner manual remover:
Delete Windows Instant Scanner files:
Protector-[rnd].exe in %AppData% folder
Delete Windows Instant Scanner registry entries:
HKEY_CURRENT_USER\Software\Microsoft\Windows\CurrentVersion\Run\
Inspector = %AppData%\Protector-[random].exe
HKEY_LOCAL_MACHINE\software\microsoft\Windows NT\CurrentVersion\Image File Execution Options\a.exe\
Debugger = svchost.exe
HKEY_LOCAL_MACHINE\software\microsoft\Windows NT\CurrentVersion\Image File Execution Options\aAvgApi.exe\
Debugger = svchost.exe
HKEY_LOCAL_MACHINE\software\microsoft\Windows NT\CurrentVersion\Image File Execution Options\AAWTray.exe\
Debugger = svchost.exe
HKEY_LOCAL_MACHINE\software\microsoft\Windows NT\CurrentVersion\Image File Execution Options\About.exe\
Debugger = svchost.exe
HKEY_LOCAL_MACHINE\software\microsoft\Windows NT\CurrentVersion\Image File Execution Options\ackwin32.exe\
Debugger = svchost.exe
HKEY_LOCAL_MACHINE\software\microsoft\Windows NT\CurrentVersion\Image File Execution Options\Ad-Aware.exe\
Debugger = svchost.exe
HKEY_LOCAL_MACHINE\software\microsoft\Windows NT\CurrentVersion\Image File Execution Options\adaware.exe\
Debugger = svchost.exe
HKEY_LOCAL_MACHINE\software\microsoft\Windows NT\CurrentVersion\Image File Execution Options\advxdwin.exe\
Debugger = svchost.exe
HKEY_LOCAL_MACHINE\software\microsoft\Windows NT\CurrentVersion\Image File Execution Options\AdwarePrj.exe\
Debugger = svchost.exe
HKEY_LOCAL_MACHINE\software\microsoft\Windows NT\CurrentVersion\Image File Execution Options\agent.exe\
Debugger = svchost.exe
HKEY_LOCAL_MACHINE\software\microsoft\Windows NT\CurrentVersion\Image File Execution Options\agentsvr.exe\
Debugger = svchost.exe
HKEY_LOCAL_MACHINE\software\microsoft\Windows NT\CurrentVersion\Image File Execution Options\agentw.exe\
Debugger = svchost.exe
HKEY_LOCAL_MACHINE\software\microsoft\Windows NT\CurrentVersion\Image File Execution Options\alertsvc.exe\
Debugger = svchost.exe
HKEY_LOCAL_MACHINE\software\microsoft\Windows NT\CurrentVersion\Image File Execution Options\alevir.exe\
Debugger = svchost.exe
HKEY_LOCAL_MACHINE\software\microsoft\Windows NT\CurrentVersion\Image File Execution Options\alogserv.exe\
Debugger = svchost.exe
HKEY_LOCAL_MACHINE\software\microsoft\Windows NT\CurrentVersion\Image File Execution Options\AlphaAV\
Debugger = svchost.exe
HKEY_LOCAL_MACHINE\software\microsoft\Windows NT\CurrentVersion\Image File Execution Options\AlphaAV.exe\
Debugger = svchost.exe
Source
Can you get into services? – Dave – 2012-10-24T11:47:58.563
2What tools have you used up to this point?
Malwarebytes
should be able to remove this spyware. – Ramhound – 2012-10-24T11:53:51.1331
+1 for Malwarebytes but if Malwarebytes doesn't work (and I assume it doesn't) then try the tutorial here in the video: http://www.2-viruses.com/remove-windows-instant-scanner - it uses SpyHunter (although there is a cost but it does show it removes the issue you have)
– Dave – 2012-10-24T11:54:33.2201
look at the canonical faq on removing malware and viruses How do I get rid of malicious spyware, malware, viruses or rootkits from my PC?
– Sathyajith Bhat – 2012-10-24T12:20:12.357