Purely anecdotal remarks, so take them for what they're worth.
A company I worked for used WD Caviar Greens for their attractive price point and lower power consumption for a number of years, and used them in both single-drive setups as well as multi-drive hardware-based RAID (1, 5, 10). Primarily the controllers were 3ware 8xxx and 9xxx series with some newer LSI models as well. We often found that the drives would be kicked out of the array either showing FAIL or more commonly just ERROR. Both cases would lead the array to become degraded, however in the latter case one could simply issue an array rebuild and the drive would pick right back up and run for quite some time without issue.
After this happened a few times on different controllers/servers, we suspected something was up with these Green drives. We dug around in the spec sheets (WD doesn't make it clear in the least from their product briefs) and found that these drives operate at 5400rpm and that is where the power savings come from. What we concluded is that the controller was seeing these units as bad when they took longer to respond than the controller expected and subsequently were dropped from the array by the controller.
Also a likely contributing factor is the lack of TLER support in these drives, so anytime there was a bad sector, the drive would also be dropped.
Furthermore, when compared to Caviar Blacks or the RE4 drives, there is a very significant IO imporvement in our tests in a 4 drive RAID10 array.
1WD does not support using Green drives in a RAID at all. So you are already being risky. In any case I strongly suggest you do not use RAID5, and instead go for RAID10, or RAID6. That way you will be at least somewhat safe when one of those drives failes. – Zoredache – 2012-04-30T19:16:26.080
1Using Green Drives is a mess. Trust me. They can work fine but they can cause a ton of issues down the road. I have personal experience with this. As far as using RAID10 that is nearly as risky as RAID5 since 2 disk fails could cause data loss. RAID6 would be the best option. But if you get abnormal slowness it's likely due to the Green drives, Get black eventually IMO. – Jeff F. – 2012-04-30T19:42:56.957
I've had the Greens in a software Mirror for over a year, and they're now in a hardware. I understand there are risks with the disks being kicked off hardware RAIDs because of timeouts, etc, but are they really so risky? Also, RAID6 and RAID10 have the same 2-disk failure tolerance; 10 is only fatal if it's the same side, granted. Sadly the controller doesn't support RAID6 and I need more than 2TB of space. – Gargravarr – 2012-04-30T20:05:08.983
The green drives' performance characteristics make them I'll-suited for a RAID. Another risk is that rebuild times are longer with larger disks, thus the chance of a second failure before the rebuild completes is also higher. Also keep in mind that any RAID configuration with parity is also susceptible to the "RAID 5 write hole," which can cause data loss. – rob – 2012-05-01T05:53:06.507