http://www.manualowl.com/m/Western%20Digital/WD3200H1U-00/Manual/131582 referance.
WD hard drive in an enclosure, It supports firewire, E-SATA, and USB.
When you say "micro USB to eSATA cable" usb and e-sata are not directally compatable, and any "cable" that would make them compatable would be an "adapter". The USB2 would always present the bandwidth limitation in any scenario where the USB is part of that chain of connections, and adapting doesnt always go very well. Therefore it would be no better than connecting up the USB itself, and way less problems.
Firewire would be quick, if you had one of those ports available.
The cable you show, is to break out a "Combo" port, do you have a sata+Usb combo port?
Yep, I do have an eSATA+USB port. – dtbarne – 2012-03-07T02:26:04.240
@dtbarne ohh , and the model of hard drive will hook up E-sata? then that should be best alone to hook up sata. and "fastest" and on a desktop (dont know about a laptop) the sata would be less load than usb. So re-reading the original question, either I got the wrong manuel :-) or you got a slimmed down version of the drive/enclosure? or I need glasses :-) – Psycogeek – 2012-03-07T04:13:33.833
If the enclosure does not support e-sata, then I would be agreeing with the other answers, and pondering getting a new enclosure, for the almost 2X speed increase of hooking it up the "best way". It would just depend on how much that was going to costs :-(, vrses the need, or the value of selling it off, and getting one of the newer ones. – Psycogeek – 2012-03-07T04:21:52.457
Yeah, it of course doesn't support eSATA. That is definitely the preferred route, was just looking to see if I could save a few bucks. Thanks for the help everyone. – dtbarne – 2012-03-07T04:57:10.627