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As far as the facts go, software installed on SSD load/work many times faster than on mechanical drives.
As far as I've heard the myth you want to install the most important stuff on the Boot drive, due to the way Microsoft works and access files and etc (that's probably not true, its just what I've heard).
Will I ever notice any performance difference between a program or game running from my boot SSD C:\ drive, compared to a regular non-boot SSD D:\ drive ?
The difference if any will be due to different speeds of the different drives. – None – 2018-01-06T19:48:56.243