msconfig - cannot save preferences (Windows 10 1703)

Trying to edit system configuration this is what happens:

Translation from italian:

System configuration: impossible to save the original startup
configuration for a future restore. Modified settings will be undone.
Impossibile to access the file. The file is used by another process

I installed Windows 10 1703 through UEFI-NTFS with Secure boot disabled and then I enabled it.
I'm using an administrative account

Edit.
The problem was caused by the HIPS (real time intrusion protection system) of Eset Nod32. And that shows HIPS works great avoiding potential malicious software making changes to the system configuration.

LppEdd

Posted 2017-10-20T08:15:29.533

Reputation: 274

Are you using any third-party security programs? – n8te – 2017-10-20T08:21:25.857

Did you try to run it with administrative privileges? – Seth – 2017-10-20T08:26:10.343

Yes I'm using Eset Nod32. And yes I've tried with admin. privileges but nothing changed. – LppEdd – 2017-10-20T09:15:06.107

Answers

This was caused by the HIPS module of NOD32 antivirus. Well apparently it works great!

LppEdd

Posted 2017-10-20T08:15:29.533

Reputation: 274

Can you be a little more clear? When you say “it works great!” are you being sarcastic? Did you discover how to save your configuration? Please do not respond in comments; [edit] your answer to make it clearer and more complete. – Scott – 2017-10-20T13:22:08.477

@Scott See updated question. – LppEdd – 2017-10-20T13:31:34.720

Disable 3rd party process/software, including anti-virus/security program(uninstall it if possible), then, re-start system and check the result.

Please confirm that if you can enable Clean Boot, if possible, re-start system in Clean Boot and try to change the MSCONFIG settings: https://support.microsoft.com/en-us/help/929135/how-to-perform-a-clean-boot-in-windows

eve wang

Posted 2017-10-20T08:15:29.533

Reputation: 293

This was partially correct. See my answer. – LppEdd – 2017-10-20T11:56:14.710