De novo

In general usage, de novo (literally 'of new') is Latin expression used in English to mean 'from the beginning', 'anew'.

De novo may also refer to:

Biology

De novo, mutation, an alteration in a gene that is present for the first time in one family member as a result of a mutation in a germ cell (egg or sperm) of one of the parents or in the fertilized egg itself
De novo, protein design, the creation of a protein sequence that is not based on existing, natural sequences
De novo protein structure prediction, the prediction of a protein's 3D structure, based only on its sequence
De novo synthesis of complex molecules from simple molecules in chemistry
De novo transcriptome assembly, the method of creating a transcriptome without a reference genome
De novo gene birth, the emergence of genes from non-coding sequence

Other

De novo review, an appellate standard of review for legal issues
Trial de novo, or a new trial in the legal system
De novo bank, a state bank that has been in operation for five years or less
De Novo, a public housing estate in Kai Tak, Hong Kong
Denovo (band), a 1980s Italian new wave group
Denovo, a supercomputer project that simulates nuclear reactions

gollark: One server I'm on actually does the rotation thing.

gollark: Alternatively, I secretly change my profile picture every hour to rotate it by 0.05 degrees, and that makes it do different things.

gollark: Oh no. It's nondeterministic too?!

gollark: (subject to conservation laws)

gollark: Weird. Someone else said red. Also, it is not in any way pizza. Those who claim it is pizza MAY be converted into arbitrary quantities of muon neutrinos if deemed necessary.

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